New insights into the pathogenesis of insulin resistance in humans using magnetic resonance spectroscopy.

Petersen, Kitt Falk; Shulman, Gerald I · Obesity (Silver Spring) · 2006

review · Level V

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Abstract

Insulin resistance plays a major role in the pathogenesis of type 2 diabetes, yet despite much effort, the underlying factors that are responsible for it are poorly understood. In this review, we focus on some recent advances in our understanding of the pathogenesis of insulin resistance in humans that have been made using magnetic resonance spectroscopy.

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