Deep-seated resistance in relapsed paratyphoid fever.

Cooke, Graham S; Cooke, Fiona J; Stone, Madeline; Turner, Keith; Al-Nahhas, Adil; Win, Zarni; Wain, John; Rogers, Thomas R et al. · Clin Infect Dis · 2006

case_report · Level V

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Abstract

We describe a case of relapsed paratyphoid fever in which the isolate had reduced susceptibility to ciprofloxacin due to a rare mutation within the gyrA gene. 18fluorodeoxyglucose positron emission tomography scanning identified deep-seated infection including unsuspected aortitis and highlights the utility of novel imaging techniques to improve our understanding and treatment of this disease.

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