The expanding cosmos of nuclear receptor coactivators.
review · Level V
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- Record sourced from PubMed, PMID 16678083.
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Abstract
About 200 coactivators play a central role in promoting gene expression mediated by nuclear receptors. This diverse group of proteins are key integrators of signals from steroid hormones and have been implicated in cancer and other diseases.
Medical subject headings
- Cell Nucleus
- Receptors, Cytoplasmic and Nuclear
- Trans-Activators
- Transcription Factors
- Transcriptional Activation