Closing the GAP between polarity and vesicle transport.

Macara, Ian G; Spang, Anne · Cell · 2006

editorial · Level V

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Abstract

How are tight junctions maintained? In this issue of Cell, Wells et al. (2006) provide intriguing evidence for a new pathway that links polarity proteins and vesicle transport to the maintenance of tight junctions, through the control of Cdc42 by Rich1, a GTPase-activating protein.

Medical subject headings