CAMTA in cardiac hypertrophy.
editorial · Level V
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- Record sourced from PubMed, PMID 16678087.
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Abstract
In this issue of Cell, the Calmodulin binding transcription activator 2 (CAMTA2), is shown by Song et al. (2006) to be an indispensable transcription coactivator for cardiac hypertrophy. CAMTA2 is activated by the dissociation of class II histone deacetylase 5 and promotes transcription of genes involved in cardiac hypertrophy through its interaction with Nkx2-5.
Medical subject headings
- Calcium-Binding Proteins
- Cardiomegaly
- Myocardium
- Myocytes, Cardiac
- Trans-Activators