A dedicated Wnt secretion factor.

Ching, Wendy; Nusse, Roel · Cell · 2006

basic_science · Level V

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Abstract

The Wnt family of signaling proteins mediates cell-cell communication during development. In this issue of Cell, Bänziger et al. (2006) and Bartscherer et al. (2006) identify Wntless/Evi, a multipass transmembrane protein in the secretory pathway of Wnt-producing cells that promotes Wnt secretion.

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