Prospective evaluation of fluorouracil chemotherapy based on the genetic makeup of colorectal cancer.

Carethers, J M · Gut · 2006

Level V

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Abstract

Evaluation of 5‐fluorouracil chemotherapy and survival, based on mismatch repair (MMR) status, indicates that patients with MMR proficient colorectal tumours benefit from 5‐fluorouracil treatment while patients with MMR deficient tumours do not

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