Rhabdomyolysis during therapy with daptomycin.

Papadopoulos, Stella; Ball, Amanda M; Liewer, Susanne E; Martin, Craig A; Winstead, P Shane; Murphy, Brian S · Clin Infect Dis · 2006

case_report · Level V

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Abstract

The use of daptomycin has been associated with an elevation in creatine phosphokinase level, with a reported incidence of 2.8% in phase III clinical trials. Published case reports have documented the presence of myopathy in patients who received daptomycin; however, there have been no previously reported cases of rhabdomyolysis in animals or humans to date. We describe a case of rhabdomyolysis during therapy with daptomycin.

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