Regulatory T cells and toll-like receptors in cancer therapy.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 16707417.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
T regulatory (Treg) cells that suppress immune responses may limit the efficiency of cancer immunotherapy. Recent findings indicate that Toll-like receptors (TLR) directly regulate the suppressive activity of Treg cells. Linking TLR signaling to the functional control of Treg cells may offer new opportunities to improve the outcome of cancer immunotherapy by coadminstration of certain TLR ligands.
Medical subject headings
- Immunotherapy
- Neoplasms
- T-Lymphocytes, Regulatory
- Toll-Like Receptors