Long-duration sCJD with PRNP codon 129 methionine homozygosity and cerebral cortical plaques.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 16707728.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The authors investigated a 40-year-old woman who presented with ataxia and dementia with little progression for over 40 months. The results of a CSF 14-3-3 protein and EEG study did not reveal major abnormalities. Brain MRI showed increased signal intensity over the occipital cortex in diffusion-weighted imaging. To our knowledge, this is the longest MM-type sporadic Creutzfeldt-Jakob disease case with cortical kuru-type plaques.
Medical subject headings
- Amyloid
- Creutzfeldt-Jakob Syndrome
- Plaque, Amyloid
- Protein Precursors