Diagnosis of lymphoma in the draining lymph node basin at the time of in-transit metastasis of cutaneous melanoma.
case_report · Level V
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Abstract
The association between cutaneous melanoma and non-Hodgkin's lymphoma (NHL) has been described. Herein we describe two cases in which lymphoma was detected in the draining lymph node basin at the time of the finding of in-transit metastasis of cutaneous melanoma. In both of these cases, sentinel lymph node biopsy at the time of the excision of the primary melanoma showed no evidence of metastatic melanoma or lymphoma. The temporal and spatial correlation of melanoma and NHL in these two cases suggests the possibility of a local failure in immune surveillance.
Medical subject headings
- Lymphoma, Non-Hodgkin
- Melanoma
- Neoplasms, Multiple Primary
- Skin Neoplasms