Neuromyelitis optica diagnosis in clinically isolated syndromes suggestive of multiple sclerosis.
retrospective_cohort · Level III
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Abstract
The authors assessed the extent of overlap between current diagnostic criteria of neuromyelitis optica (NMO) and multiple sclerosis (MS) by applying NMO criteria to a large cohort of 320 patients with clinically isolated syndromes (CIS). Twenty-three (7.2%) patients fulfilled NMO absolute criteria at some time and 1 (0.3%) also fulfilled one major supportive criterion. Therefore, even by systematically applying NMO criteria in patients with CIS, NMO diagnosis is reached infrequently.
Medical subject headings
- Multiple Sclerosis
- Myelitis
- Neuromyelitis Optica
- Optic Neuritis