Quality control in self/nonself discrimination.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 16751096.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Unicellular eukaryotes primarily employ self/nonself discrimination to avoid self-mating, whereas multicellular organisms also use self/nonself discrimination in immune defense. Recent advances in understanding self/nonself discrimination in eukaryotes shed new light on the emergence of the most sophisticated self/nonself discrimination system known, the antigen receptors employed in the adaptive immune system.
Medical subject headings
- Eukaryotic Cells
- Immunity, Innate
- Immunologic Surveillance
- Receptors, Antigen