Sulphasalazine-induced reversible hypersensitivity pneumonitis and fatal fibrosing alveolitis: report of two cases.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 1675246.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The cases of two patients with ulcerative colitis are described who developed pulmonary infiltrates during the early months of treatment with sulphasalazine. The first patient had a hypersensitivity pneumonitis, which was confirmed by challenge. Recovery was complete. The second patient developed a fibrosing alveolitis type reaction, with fatal outcome.
Medical subject headings
- Adult
- Alveolitis, Extrinsic Allergic
- Alveolitis, Extrinsic Allergic/etiology
- Colitis, Ulcerative
- Colitis, Ulcerative/drug therapy
- Female
- Humans
- Male
- Middle Aged
- Prognosis
- Pulmonary Fibrosis
- Pulmonary Fibrosis/chemically induced
- Sulfasalazine
- Sulfasalazine/adverse effects