JC virus detection in bodily fluids: clues to transmission.

Berger, Joseph R; Miller, Craig S; Mootoor, Yunanan; Avdiushko, Sergei A; Kryscio, Richard J; Zhu, Hua · Clin Infect Dis · 2006

case_control · Level III

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Abstract

JC virus in saliva, oropharyngeal fluid, blood, and urine samples obtained from 58 human immunodeficiency virus-infected persons and 58 matched controls was investigated by performing quantitative polymerase chain reaction. JC virus was rarely present in oropharyngeal fluid and blood samples, even in those obtained from immunosuppressed individuals, but it was commonly detected in urine samples from both groups, suggesting that urine contributes to transmission.

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