A ticket to the gut for thymic T cells.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 16766746.
- Also identified by PMC identifier 1856347.
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Abstract
The intestinal epithelium is colonised by, among other cells, normal T helper and cytotoxic T cells which obtain their antigen experience in the gut associated lymphatics after migration from the thymus. New evidence suggests a CD8 positive T cell that directly migrates to the intestinal epithelium increasing the role of the thymus in shaping intestinal immunity
Medical subject headings
- CD8-Positive T-Lymphocytes
- Intestinal Mucosa
- Thymus Gland