Hedgehog Wnteraction in colorectal cancer.

van den Brink, G R; Hardwick, J C H · Gut · 2006

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Abstract

The Hedgehog pathway was recently shown to antagonise constitutive activity of the Wnt pathway that drives proliferation of colorectal cancer cells. Studies in this issue of <i>Gut</i> refine our understanding of the underlying mechanism and provide evidence for such antagonism in colorectal cancers in vivo

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