Secondary transmission of varicella vaccine virus in a chronic care facility for children.

Grossberg, Richard; Harpaz, Rafael; Rubtcova, Elena; Loparev, Vladimir; Seward, Jane F; Schmid, D Scott · J Pediatr · 2006

case_report · Level V

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Abstract

A 16-year-old varicella-seronegative resident at a chronic care facility received varicella vaccine; 15 days later he developed severe varicella. Subsequently, a 13-year-old resident and a 39-year-old health care worker developed mild varicella. We demonstrate that vaccine-strain virus was transmitted to both persons, and that transmission included at least 2 variant vaccine strains.

Medical subject headings