Glomeruloid hemangioma leading to a diagnosis of POEMS syndrome.

Phillips, Julie A; Dixon, Julie E; Richardson, Jeffrey B; Fabre, Vilma C; Callen, Jeffrey P · J Am Acad Dermatol · 2006

case_report · Level V

Where this comes from

Abstract

POEMS is an acronym for polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, and skin changes. It is a poorly understood paraneoplastic syndrome that stems from an underlying plasma cell dyscrasia. Of the skin changes, the glomeruloid hemangioma is considered to be a specific marker of POEMS syndrome. We describe a 68-year-old man who presented to his dermatologist with multiple hemangiomas, whose biopsy diagnosis of glomeruloid hemangioma resulted in further evaluation and an eventual diagnosis of POEMS.

Medical subject headings