Life-threatening sepsis caused by Burkholderia cepacia from contaminated intravenous flush solutions prepared by a compounding pharmacy in another state.

Held, Melissa R; Begier, Elizabeth M; Beardsley, Diana S; Browne, Frederick A; Martinello, Richard A; Baltimore, Robert S; McDonald, L Clifford; Jensen, Bette et al. · Pediatrics · 2006

case_report · Level V

Where this comes from

Abstract

We report 2 life-threatening cases of Burkholderia cepacia sepsis caused by infusate contamination during compounding. Bacterial isolates from the patients' blood cultures and the infusate were indistinguishable by pulsed-field gel electrophoresis. Proper quality controls at a local and national level are important for ensuring safe delivery of compounded medications to patients in all settings, including those outside health care facilities.

Medical subject headings