Survival probability in ataxia telangiectasia.

Crawford, T O; Skolasky, R L; Fernandez, R; Rosquist, K J; Lederman, H M · Arch Dis Child · 2006

retrospective_cohort · Level III

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Abstract

Ataxia telangiectasia is a rare, multiorgan neurodegenerative disorder with enhanced vulnerability to cancer and infection. Median survival in two large cohorts of patients with this disease, one prospective and one retrospective, is 25 and 19 years, with a wide range. Life expectancy does not correlate well with severity of neurological impairment.

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