Brain atrophy after immunoablation and stem cell transplantation in multiple sclerosis.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 16801665.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
The authors measured brain atrophy in nine patients undergoing immunoablation and autologous hematopoietic stem cell transplantation for multiple sclerosis. From baseline to 1 month after treatment, atrophy was 10 times faster than before treatment. A patient with non-CNS lymphoma showed comparable acute brain atrophy after analogous therapy. These observations suggest that brain atrophy after immunoablation may not be due entirely to the resolution of edema but may be related to chemotoxicity.
Medical subject headings
- Brain
- Brain Diseases
- Immunosuppression Therapy
- Immunosuppressive Agents
- Multiple Sclerosis
- Stem Cell Transplantation