Eicosapentapeptide repeats (EPRs): novel repeat proteins specific to flowering plants.
basic_science · Level V
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Abstract
In this report, we describe a novel tandem peptide repeat protein, Eicosapentapeptide repeat (EPR), which occurs notably only in flowering plants. The EPRs are characterized by a 25 amino acid repeat unit, X(2)CX(4)CX(10)CX(2)HGGG, repeated 10 times tandemly. Sequence search revealed that the repeat motif is highly conserved across its occurrence. EPRs are predicted to exist as quasi-globular stable structures owing to highly conserved amino acid positions and potential disulfide bridges. Proteins containing EPRs are predicted to be located in chloroplasts; non-enzymatic and peptide or DNA-binding in molecular function; and they are possibly involved in transcription regulation.
Medical subject headings
- Flowers
- Oryza
- Peptides
- Plant Proteins
- Sequence Alignment
- Sequence Analysis, Protein