Gene amplification: yeast takes a turn.

Haber, James E; Debatisse, Michelle · Cell · 2006

review · Level V

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Abstract

The origins of gene amplifications in mammalian cells have been difficult to analyze because of secondary genome rearrangements. Recent studies in budding yeast, including in this issue of Cell, have provided new insights into the role of palindromic sequences in gene amplification.

Medical subject headings