Designer macrophages: oxidative metabolism fuels inflammation repair.
review · Level V
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Abstract
Macrophages play a central role in immunity, contributing to both the initiation and resolution of inflammation. In this issue of Cell Metabolism, Vats et al. provide insight into the mechanisms by which reparative macrophages are generated and reveal a previously unappreciated link between this anti-inflammatory axis and mitochondrial oxidative metabolism (Vats el al., 2006).
Medical subject headings
- Energy Metabolism
- Inflammation
- Macrophages