Fungal keratitis associated with non-therapeutic soft contact lenses.

Alfonso, Eduardo C; Miller, Darlene; Cantu-Dibildox, Jorge; O'brien, Terrence P; Schein, Oliver D · Am J Ophthalmol · 2006

retrospective_cohort · Level III

Where this comes from

Abstract

To report an increase in culture-positive contact lens-associated fungal keratitis. Retrospective, cross-sectional laboratory study. Microbiology records of culture-positive fungal keratitis cases from January 2004 to December 2005 were reviewed. Recovery of fungal pathogens among wearers of contact lenses increased from 26.7% (eight of 30) to 50% (18 of 36) of isolates in 2005. Fusarium species (66 of 122, 54.1%) were the most frequent fungal pathogens. Soft contact lens wear among the Fusarium cases more than doubled (seven of 30, 23.3%, vs 17 of 36, 47.7%, P = .046) from 2004 to 2005. Contact lens wear may be a risk factor in fungal keratitis.

Medical subject headings