Dynamic contrast-enhanced magnetic resonance imaging as an imaging biomarker.
review · Level V
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Abstract
Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is being used in oncology as a noninvasive method for measuring properties of the tumor microvasculature. There is potential for DCE-MRI to be used as an imaging biomarker to measure antiangiogenic effects of cancer treatments. This article reviews the general methodology for performing DCE-MRI and discusses existing data and challenges to applying DCE-MRI for treatment response assessment in clinical trials.
Medical subject headings
- Biomarkers, Tumor
- Contrast Media
- Magnetic Resonance Imaging
- Neoplasms