Hippocampal abnormalities and seizure recurrence after antiepileptic drug withdrawal.

Cardoso, T A M; Coan, A C; Kobayashi, E; Guerreiro, C A M; Li, L M; Cendes, F · Neurology · 2006

prospective_cohort · Level II

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Abstract

The authors performed hippocampal volumetry and T2 relaxometry in 84 consecutive patients with partial epilepsy from a protocol for antiepileptic drug (AED) withdrawal after at least 2 years of seizure control. Seizure recurrence after AED withdrawal was more frequent among patients with hippocampal atrophy and abnormal hippocampal T2 signal.

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