Functional DNAzymes organized into two-dimensional arrays.
basic_science · Level V
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- Record sourced from PubMed, PMID 16834439.
- Also identified by PMC identifier 2536694.
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Abstract
DNAzymes are catalytically active DNA molecules, which have previously been described in solution. Here, we organize these molecules into a series of two-dimensional (2D) arrays using a periodic arrangement of DNA structures based on the DNA double crossover motif. We demonstrate by means of atomic force microscopy that the DNAzymes are organized according to the design and that they retain their activity when attached in linear strings within the context of the 2D array.
Medical subject headings
- DNA, Catalytic
- Nanotechnology
- Oligonucleotide Array Sequence Analysis