In search of an optimum dose escalation for narrowband UVB phototherapy: is it time to quit 20% increments?
retrospective_cohort · Level III
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Abstract
Our aim was to compare 20% with 10% to 5% incremental regimens in narrowband UVB phototherapy. The study included patients with psoriasis (N = 191) with Fitzpatrick skin phototypes II and III. Occurrence of erythema as well as maximum and cumulative doses were higher with 20% escalations, whereas response rates and time to response did not significantly differ. The study was limited by its retrospective nature. A 5% or 10% incremental regimen may have similar therapeutic efficacy.
Medical subject headings
- Phototherapy
- Psoriasis
- Ultraviolet Rays