Interfering with interferons in inflammatory bowel disease.

Ghosh, S; Chaudhary, R; Carpani, M; Playford, R · Gut · 2006

review · Level V

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Abstract

Early experience of fontolizumab, a humanised anti‐interferon γ antibody, in active Crohn's disease has shown that the drug caused a significant decrease in endoscopic severity scores and CRP and was reasonably well tolerated. Fontolizumab may be worthy of further clinical trials

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