An experimental metagenome data management and analysis system.

Markowitz, Victor M; Ivanova, Natalia; Palaniappan, Krishna; Szeto, Ernest; Korzeniewski, Frank; Lykidis, Athanasios; Anderson, Iain; Mavromatis, Konstantinos et al. · Bioinformatics · 2006

basic_science · Level V

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Abstract

The application of shotgun sequencing to environmental samples has revealed a new universe of microbial community genomes (metagenomes) involving previously uncultured organisms. Metagenome analysis, which is expected to provide a comprehensive picture of the gene functions and metabolic capacity for microbial communities, needs to be conducted in the context of a comprehensive data management and analysis system. We present in this paper IMG/M, an experimental metagenome data management and analysis system that is based on the Integrated Microbial Genomes (IMG) system. IMG/M provides tools and viewers for analyzing both metagenomes and isolate genomes individually or in a comparative context. IMG/M is available at http://img.jgi.doe.gov/m.

Medical subject headings