Distal phalange necrosis: a severe manifestation of palmar plantar erythrodysesthesia.

Palaia, Innocenza; Angioli, Roberto; Bellati, Filippo; Basile, Stefano; Rabitti, Carla; Panici, Pierluigi Benedetti · Am J Obstet Gynecol · 2006

case_report · Level V

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Abstract

Palmar plantar erythrodysesthesia is a cutaneous drug reaction induced by chemotherapy. We present a case of a patient with neurosensorial deficit affected by ovarian cancer who experienced a painless necrosis of a distal phalange of the hand during treatment with pegylated liposomal doxorubicin. Palmar plantar erythrodysesthesia may be underestimated by physicians in paucisymptomatic patients.

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