GenePro: a Cytoscape plug-in for advanced visualization and analysis of interaction networks.
basic_science · Level V
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- Record sourced from PubMed, PMID 16921162.
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Abstract
Analyzing the networks of interactions between genes and proteins has become a central theme in systems biology. Versatile software tools for interactively displaying and analyzing these networks are therefore very much in demand. The public-domain open software environment Cytoscape has been developed with the goal of facilitating the design and development of such software tools by the scientific community. We present GenePro, a plugin to Cytoscape featuring a set of versatile tools that greatly facilitates the visualization and analysis of protein networks derived from high-throughput interactions data and the validation of various methods for parsing these networks into meaningful functional modules. The GenePro plugin is available at the website http://genepro.ccb.sickkids.ca.
Medical subject headings
- Algorithms
- Models, Biological
- Protein Interaction Mapping
- Proteome
- Signal Transduction
- Software
- User-Computer Interface