Dominantly transmitted focal dystonia in families of patients with musician's cramp.

Schmidt, A; Jabusch, H-C; Altenmüller, E; Hagenah, J; Brüggemann, N; Hedrich, K; Saunders-Pullman, R; Bressman, S B et al. · Neurology · 2006

case_series · Level IV

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Abstract

Musician's dystonia is generally considered a sporadic disorder. We present three families with the index patient affected by musician's dystonia, but other forms of upper limb focal task-specific dystonia (FTSD), mainly writer's cramp, in seven relatives. Our results suggest a genetic contribution to FTSD with phenotypic variability, including musician's dystonia.

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