Making sense of the sensor: mysteries of the macula densa.
editorial · Level V
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- Record sourced from PubMed, PMID 16929331.
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Abstract
Increases in luminal NaCl concentration at the macula densa (MD), the sensing element, activate tubuloglomerular feedback (TGF). MD cell volume increases when increments are isosmotic and shrinks if osmolality increases. This interesting finding introduces additional complexity to the role of the MD in TGF.
Medical subject headings
- Cell Size
- Feedback, Physiological
- Kidney Glomerulus
- Kidney Tubules, Distal