Is the slippery slope from steatosis to steatohepatitis paved with triglyceride or cholesterol?
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 16950134.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Accumulation of hepatic lipids has been thought to trigger the inflammation, apoptosis, and fibrosis that characterize progression of hepatic steatosis to steatohepatitis and cirrhosis. In this issue of Cell Metabolism, Marí et al. (2006) provide evidence for excessive mitochondrial free cholesterol as a cause of the progession of steatosis to more severe liver disease.
Medical subject headings
- Cholesterol
- Fatty Liver
- Hepatitis
- Lipid Metabolism
- Liver
- Triglycerides