An ARC light on lipid metabolism.
review · Level V
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Abstract
The SREBP pathway plays a central role in the regulation of lipid metabolism. In a recent letter, Yang et al. present a comprehensive series of experiments, spanning a wide range of disciplines, that identify ARC105 as a component of the ARC complex that interacts directly with SREBP and is necessary for SREBP function (Yang et al., 2006).
Medical subject headings
- Lipid Metabolism
- Sterol Regulatory Element Binding Proteins
- Transcription Factors