Life-threatening bleomycin pulmonary toxicity with ultimate reversibility.
case_report · Level V
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- Record sourced from PubMed, PMID 1695873.
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Abstract
A 60-year-old man with advanced seminoma was treated with four cycles of a cisplatin, etoposide and bleomycin. He then developed severe pulmonary toxicity with diffuse infiltrates as evidenced on a chest x-ray film. The room air PaO2 value was 32 mm Hg. The patient was treated with steroids and oxygen supplementation, including a high FIo2 for several days, and survived and eventually experienced marked improvement in his pulmonary status. Aggressive management of severe bleomycin-induced pneumonitis appears justified.
Medical subject headings
- Bleomycin
- Pneumonia