Refsum's disease: electron microscopy of an iris biopsy.

Dick, A D; Jagger, J; McCartney, A C · Br J Ophthalmol · 1990

case_report · Level V

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Abstract

Refsum's disease (phytanic acid storage disease) results in an accumulation of lipid as a result of an absence of mitochondrial hydroxylation of phytanic acid. We describe a previously unrecorded electron microscopic study of lipid deposition in the iris pigment epithelium of a patient with Refsum's disease, and lipid was present in other sites within the iris.

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