Augur--a computational pipeline for whole genome microbial surface protein prediction and classification.
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Abstract
The analysis of protein function is a challenge and a major bottleneck towards well-annotated and analysed microbial genomes. In particular, bacterial surface proteins present an opportunity for pharmacological intervention and vaccine development. We present Augur, an automatic prediction pipeline that integrates major surface prediction algorithms and enables comparative analysis, classification and visualization for gram-positive bacteria on a genomic scale. http://bioinfo.mikrobio.med.uni-giessen.de/augur
Medical subject headings
- Computational Biology
- Genome, Bacterial
- Membrane Proteins
- Proteomics