Late-onset Tay-Sachs disease: adverse effects of medications and implications for treatment.
retrospective_cohort · Level III
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- Record sourced from PubMed, PMID 16966555.
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Abstract
The authors conducted a retrospective and brief prospective study of adverse effects of approximately 350 medications in 44 adults with late-onset Tay-Sachs disease (LOTS). Some medications were relatively safe, whereas others, particularly haloperidol, risperidone, and chlorpromazine, were associated with neurologic worsening.
Medical subject headings
- Psychotropic Drugs
- Tay-Sachs Disease