The investigation and management of chronic neutropenia in children.

James, R M; Kinsey, S E · Arch Dis Child · 2006

review · Level V

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Abstract

Unravelling the cause of a neutropenia poses a complex diagnostic challenge. The differential diagnosis ranges from life threatening disease to transient benign causes of little clinical significance. This review offers a practical guide to investigating the neutropenic child, and highlights features that merit specialist referral. Therapeutic options, the role of long term follow up, and the complications of severe chronic neutropenia are considered.

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