Myocardial injury in patients with intracerebral hemorrhage treated with recombinant factor VIIa.

Sugg, R M; Gonzales, N R; Matherne, D E; Ribo, M; Shaltoni, H M; Baraniuk, S; Noser, E A; Grotta, J C · Neurology · 2006

retrospective_cohort · Level III

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Abstract

We report myocardial injury in 20 recombinant factor VIIa (rFVIIa) treated and 110 nontreated patients with intracerebral hemorrhage. Patients were treated or received standard medical management. All received EKG and cardiac enzyme testing. Elevated troponin occurred in 20% treated vs 3% nontreated (p = 0.02). Myocardial infarction occurred in 10% vs 1% (p = 0.01). We found a significant increase in myocardial injury in rFVIIa treated patients.

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