Horizons in prosthesis development for the restoration of limb function.

Aaron, Roy K; Herr, Hugh M; Ciombor, Deborah McK; Hochberg, Leigh R; Donoghue, John P; Briant, Clyde L; Morgan, Jeffrey R; Ehrlich, Michael G · J Am Acad Orthop Surg · 2006

review · Level V

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Abstract

The focus of our research program is the restoration of limb function through a biohybrid approach. We consider the limb conceptually as a biohybrid organ consisting of biological tissue, endoprostheses (including neural devices and joint replacements), and exoprostheses. The biohybrid limb maximizes biological function and functional articulations with optimized human-prosthesis interfaces. Our long-term goals are to create biomimetic prostheses, optimized control systems for prostheses, and optimized human-prosthesis interfaces using both limb lengthening and osseointegration techniques.

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