Myofibroblastoma of the tongue. An immunohistochemical, ultrastructural, and flow cytometric study.

Sahin, A A; Ro, J Y; Ordoñez, N G; Luna, M A; el-Naggar, A K; Goepfert, H; Ayala, A G · Am J Clin Pathol · 1990

case_report · Level V

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Abstract

A case of myofibroblastoma arising in the tongue of a 77-year-old man is described. The patient presented with a submucosal tongue mass without other associated symptoms. The tumor was 2 cm in diameter, well circumscribed, and composed of uniform spindle cells arranged in fascicles. Electron microscopic examination and immunohistochemistry demonstrated a myofibroblastic origin for the tumor cells. DNA flow cytometric analysis showed a diploid DNA content of this tumor. To the authors' knowledge, this is the first report of myofibroblastoma occurring in the tongue.

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