Regulation of ribosome biogenesis: where is TOR?
review · Level V
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Abstract
Li et al., (2006) have shown that TOR complex 1 in yeast binds directly to the rDNA promoter and thereby activates Pol I-dependent synthesis of 35S RNA. This is an important advance in the understanding of how ribosome biogenesis is regulated in response to environmental conditions.
Medical subject headings
- Phosphatidylinositol 3-Kinases
- Phosphotransferases (Alcohol Group Acceptor)
- RNA
- Ribosomes
- Saccharomyces cerevisiae Proteins