The key to left-right asymmetry.

Tabin, Clifford J · Cell · 2006

review · Level V

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Abstract

Establishment of left-right asymmetry in vertebrates involves cilia as essential components in the breaking of symmetry, an asymmetric signaling cascade, and a midline barrier that helps to maintain asymmetry. A new study suggests that a reaction-diffusion mechanism also plays a key role.

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