Regulation of ENaCs by proteases: An increasingly complex story.
editorial · Level V
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Abstract
Proteolytic processing of epithelial Na+ channel (ENaC) subunits has an important role in the regulation of ENaC gating. This Commentary addresses the potential roles of specific proteases and protease inhibitors in the control of Na+ channel gating.
Medical subject headings
- Amyloid beta-Protein Precursor
- Peptide Hydrolases
- Receptors, Cell Surface
- Sodium Channels