Elevated CSF free kappa light chains correlate with disability prognosis in multiple sclerosis.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 17030770.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Elevated CSF free kappa light chains (FKLCs) may predict disability in multiple sclerosis (MS). We reviewed records of 57 patients with MS with 15-year median follow-up for correlations of disability and CSF FKLCs. Levels > or = 1.53 microg/mL predicted progression to need for ambulatory assistance during follow-up (specificity 87.5%, positive predictive value 88.9%) or within 10 years (specificity 78.6%, positive predictive value 66.7%).
Medical subject headings
- Disability Evaluation
- Health Status Indicators
- Immunoglobulin kappa-Chains
- Multiple Sclerosis